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How Much Sodium Is in a Loaded Meat Slice? 5 Chains Compared

by The Pizza Guy | Jul 1, 2026 | Healthy Pizza Guides

Cheese pizza on a plate
Pizza Nutrition · 5 National Chains · One Loaded Slice

One meat slice, half a day’s salt.

Pile five meats onto a slice and the calories barely move. The sodium is another story — a single slice of the saltiest option carries 1,040 mg, close to half a full day’s limit before you reach for a second.

Analysis & data compiled July 1, 2026 · Signature meat pizza, one large slice, from each chain’s published nutrition data · Sources in full below
One loaded slice, across 5 chains lowest → highest
The Quick Version

One slice of a chain’s signature meat pizza carries 776–1,040 mg of sodium — 34% to 45% of the FDA’s 2,300 mg daily limit. Calories stay tight (346–390), so the meats’ real cost is salt, not size. Two slices pushes most chains past two-thirds of a day’s sodium.

  • Papa John’s tops the set. The Meats delivers 1,040 mg in one slice — about 45% of the daily limit.
  • Every meat slice clears a third of a day’s sodium. The lowest, Little Caesars’ 3 Meat Treat, is still 776 mg.
  • Calories barely move. Just 44 calories separate the highest slice from the lowest.
  • Two slices runs 67–90% of your daily sodium before a drink or a side.
  • The upside is protein: 15–20 g per slice from all that meat.
The data

Every number, one table

Each chain’s signature all-meat pizza, one slice of a large, standard crust, as published. “% daily” is the share of the FDA’s 2,300 mg sodium limit in a single slice. Tap a column to sort.

Chain Calories Fat (g) Sodium (mg) ▾ % daily Protein (g)
Two views

Salt is the variable

Sodium per slice

milligrams · one slice of the signature meat pizza

Two slices vs your daily limit

share of the 2,300 mg FDA sodium limit — from two slices alone

Calories per slice

for contrast — the number that barely moves
Reading the numbers

Watch the salt,
not the calories

Ranked by calories, these five meat slices finish within 44 of each other — effectively a tie. Ranked by sodium, they spread from 776 to 1,040 mg, and every one of them puts a third to nearly half a day’s sodium into a single slice. The meats you can taste are doing less to the calorie count than the salt you can’t.

The reason is cured meat. Pepperoni, sausage, bacon, and ham are salt-preservation systems as much as they are toppings, so stacking several of them onto one slice moves sodium far more than it moves calories. That’s why the loaded slice looks so ordinary on a calorie tracker and so heavy on a sodium one — and why two slices, a number most people clear without thinking, can account for the majority of a day’s sodium on their own.

The trade you’re actually making

It isn’t all cost. A meat slice carries 15 to 20 grams of protein, more than a plain cheese slice, which is why these pizzas feel satisfying. The honest read is a trade: more protein and a lot more sodium, for almost no change in calories. If sodium is the number you watch, one meat slice alongside a plainer second is a better split than two of the same — and the water, not a soda, keeps the day’s total in range.

How this was built

Methodology & sources

Reference product
One slice of each chain’s signature all-meat pizza on a large, standard crust (hand-tossed, original, or classic round). Godfather’s is its Original-crust All-Meat Combo. Slice cut counts differ by chain, the usual caveat of any per-slice comparison.
Sources
Each value comes from the chain’s published nutrition data or a nutrition resource reproducing it, cited per chain below. Sodium was verified for every row — no value is estimated.
% daily sodium
Calculated against the FDA’s 2,300 mg daily reference for adults. Two-slice figures are simply doubled.
Known limits
Values reflect standard menu recipes and can vary by location, franchise, crust, and reformulation. Collected July 2026.
  • Papa John’s — The Meats, Original, large, 1 slice: 380 cal, 1,040 mg sodium. Papa John’s data via Nutrition & Ingredients
  • Godfather’s — All-Meat Combo, Original, large 1/10 slice (161 g): 390 cal, 890 mg sodium. Godfather’s Nutritional Guide (PDF)
  • Domino’s — MeatZZa, hand-tossed, large 1/8 slice: 370 cal, 850 mg sodium. Domino’s data via Eat This, Not That
  • Pizza Hut — Meat Lover’s, hand-tossed, large 1/8 slice: 390 cal, 830 mg sodium. Pizza Hut nutrition
  • Little Caesars — 3 Meat Treat, large 1/8 slice: 346 cal, 776 mg sodium. Little Caesars data via FastFoodNutrition
More on pizza & health
  • Pizza Nutrition, Compared: 5 Chains, One Cheese Slice
  • Can You Eat Pizza on a Diet? I Did the Math.
  • The Toppings That Turn Pizza Into a High-Protein Meal
  • Why Pizza Is Better Post-Workout Than You’ve Been Told

Figures compiled from publicly available nutrition data for informational purposes and are not a substitute for professional dietary advice. Sodium needs vary by individual; the 2,300 mg reference is a general FDA guideline. Nutrition information can change without notice and vary by location. Data collected July 1, 2026.

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Godfather's Pizza San Antonio
8530 TX-151, San Antonio, TX 78245
Phone: (210) 750-2222

2,000 CALORIES A DAY IS USED FOR GENERAL NUTRITION ADVICE, BUT CALORIE NEEDS VARY. ADDITIONAL NUTRITION INFORMATION AVAILABLE UPON REQUEST.